Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.

@article{Dominski2005DifferencesAS,
  title={Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.},
  author={Zbigniew Dominski and Xiao-cui Yang and Mathew Purdy and William Bill F Marzluff},
  journal={RNA},
  year={2005},
  volume={11 12},
  pages={1835-47}
}
We used nuclear extracts from Drosophila Kc cells to characterize 3' end processing of Drosophila histone pre-mRNAs. Drosophila SLBP plays a critical role in recruiting the U 7 snRNP to the pre-mRNA and is essential for processing all five Drosophila histone pre-mRNAs. The Drosophila processing machinery strongly prefers cleavage after a fourth nucleotide… CONTINUE READING