Difference in the way of macrophage recognition of target cells depending on their apoptotic states

@article{Fujii2001DifferenceIT,
  title={Difference in the way of macrophage recognition of target cells depending on their apoptotic states},
  author={Chifumi Fujii and Akiko Shiratsuchi and Junko Manaka and Shin Yonehara and Yoshinobu Nakanishi},
  journal={Cell Death and Differentiation},
  year={2001},
  volume={8},
  pages={1113-1122}
}
Dying cells are selectively eliminated from the organism by phagocytosis. Previous studies suggested the existence of some other phagocytosis marker(s) that function together with phosphatidylserine, the best-characterized phagocytosis marker. We obtained here a monoclonal antibody named PH2 that inhibited macrophage phagocytosis of late apoptotic or… CONTINUE READING