Difference in interaction of fibronectin with type I collagen and type IV collagen.

@article{Shimizu1997DifferenceII,
  title={Difference in interaction of fibronectin with type I collagen and type IV collagen.},
  author={Masumi Shimizu and Kazuo Minakuchi and Myung-soon Moon and Jinichiro Koga},
  journal={Biochimica et biophysica acta},
  year={1997},
  volume={1339 1},
  pages={53-61}
}
In our studies on fibronectin, difference in binding to type I collagen and type IV collagen was observed and analysed. Four different fragments, which consist of I6-II1-II2-I7-I8-I9, I6-II1-II2-I7, I6-II1-II2, and I8-I9 within the collagen binding domain, have been isolated from proteolytic digests of fibronectin. The N-terminal fragments of the collagen binding domain showed the binding affinity to both of type I and type IV collagens. On the other hand, the C-terminal portion of the domain… CONTINUE READING