Difference in dilatation between endothelium-preserved and -desquamated segments in the flow-loaded rat common carotid artery.

@article{Tohda1992DifferenceID,
  title={Difference in dilatation between endothelium-preserved and -desquamated segments in the flow-loaded rat common carotid artery.},
  author={K Tohda and Hirotake Masuda and Keiichi Kawamura and Takeshi Shozawa},
  journal={Arteriosclerosis and thrombosis : a journal of vascular biology},
  year={1992},
  volume={12 4},
  pages={519-28}
}
To study arterial dilatation in response to increased flow, we observed the bilateral common carotid arteries (CCAs) of 10 16-week-old rats that were maintained for 8 weeks after construction of an arteriovenous (AV) fistula between the left CCA and the jugular vein at a level 20 mm distal from the aortic orifice. The flow in the left CCA increased 11-fold and that of the right CCA increased twofold compared with values before surgery. The left CCA showed complete desquamation of endothelial… CONTINUE READING
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