Dietary zinc alters early inflammatory responses during cutaneous wound healing in weanling CD-1 mice.

@article{Lim2004DietaryZA,
  title={Dietary zinc alters early inflammatory responses during cutaneous wound healing in weanling CD-1 mice.},
  author={Yunsook Lim and Mark A Levy and Tammy M. Bray},
  journal={The Journal of nutrition},
  year={2004},
  volume={134 4},
  pages={811-6}
}
Zinc deficiency is a well-known health problem associated with delayed wound healing, yet the precise mechanisms that underlie the delay remain unknown. We hypothesized that zinc deficiency delays wound healing as a result of decreased nuclear factor (NF)kappaB activation, reduced expression of proinflammatory cytokines [interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha], and a decrease in neutrophil infiltration during the early stage of cutaneous wound healing. We used a cutaneous… CONTINUE READING

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