Dietary treatment in adults with refractory epilepsy

  title={Dietary treatment in adults with refractory epilepsy},
  author={Pavel Klein and Ivana Tyrl{\'i}kov{\'a} and Gregory C. Mathews},
  pages={1978 - 1985}
We review adjunctive ketogenic diet (KD) and modified Atkins diet (MAD) treatment of refractory epilepsy in adults. Only a few studies have been published, all open-label. Because of the disparate, uncontrolled nature of the studies, we analyzed all studies individually, without a meta-analysis. Across all studies, 32% of KD-treated and 29% of MAD-treated patients achieved ≥50% seizure reduction, including 9% and 5%, respectively, of patients with >90% seizure frequency reduction. The effect… 

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