Dietary trans fatty acids increase serum cholesterylester transfer protein activity in man.

@article{Tol1995DietaryTF,
  title={Dietary trans fatty acids increase serum cholesterylester transfer protein activity in man.},
  author={Arie van Tol and Peter L. Zock and Teus van Gent and Leo M Scheek and Martijn Bernard Katan},
  journal={Atherosclerosis},
  year={1995},
  volume={115 1},
  pages={129-34}
}
The average diet may provide some 8-10 g/day of unsaturated fatty acids with a trans double bond. Previous studies showed that dietary trans fatty acids may simultaneously raise low-density lipoprotein (LDL) cholesterol and reduce high-density lipoprotein (HDL) cholesterol. Human plasma contains a protein (CETP) which transfers cholesterylesters from HDL to lipoproteins of lower density. We hypothesized that CETP could play a role in the effect of trans fatty acids on lipoproteins and measured… CONTINUE READING