Dietary trans fatty acids: Review of recent human studies and food industry responses

@article{Hunter2006DietaryTF,
  title={Dietary trans fatty acids: Review of recent human studies and food industry responses},
  author={J. Edward Hunter},
  journal={Lipids},
  year={2006},
  volume={41},
  pages={967-992}
}
  • J. E. Hunter
  • Published 1 November 2006
  • Chemistry, Medicine
  • Lipids
Dietary trans FA at sufficiently high levels have been found to increase low density lipoprotein (LDL)-cholesterol and decrease high density lipoprotein (HDL)-cholesterol (and thus to increase the ratio of LDL-cholesterol/HDL-cholesterol) compared with diets high in cis monounsaturated FA or PUFA. The dietary levels of trans FA at which these effects are easily measured are around 4% of energy or higher to increase LDL-cholesterol and around 5 to 6% of energy or higher to decrease HDL… Expand
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99 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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99 Citations

Citation Type

Citation Type

Industrial Trans Fatty Acid and Serum Cholesterol: The Allowable Dietary Level
TLDR
The relationship between dietary industrial TFAs and concentration of plasma cholesterol should be evaluated from the viewpoint of dietary patterns rather than TFAs alone. Expand
Trans fatty acids (tFA): sources and intake levels, biological effects and content in commercial Spanish food.
TLDR
The results show that major sources of trans fatty acids in commercial Spanish foods are fast-food (hamburger, French fries), snacks, bakery products (cakes, donuts, biscuits), margarines and dehydrated soups. Expand
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It appears that few dose-response data points are available to assess the relationship of low levels of iTFA, particularly from PHO exposure, and LDL-C, and limited evidence is available to determine the effect of iT FA at current consumption levels on CHD risk. Expand
Little Effect of Supplementation with 0.6% Energy Trans Fatty Acids on Serum Cholesterol Levels in Adult Japanese Women.
TLDR
Results confirm that dietary supplementation with 0.6%E TFAs (a total TFA intake of approximately 1%E) would have little effect on serum cholesterol levels in healthy adult Japanese women. Expand
Supplementation with 1% Energy Trans Fatty Acids Had Little Effect on Serum Cholesterol Levels in Healthy Young Japanese Women
TLDR
The results suggest that energy of TFAs at less than 1% has little effect on serum cholesterol or hemoglobin A1c levels in healthy young women, and confirms the correctness of the WHO recommendation. Expand
Health and nutrition update on trans fatty acids
TLDR
Overall, during the last 10 or more years, there has been a major reduction in TFA levels in the U.S. food supply, and efforts continue to reduce these levels further. Expand
Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review.
TLDR
The replacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats beneficially affects LDL cholesterol, the primary target for CVD risk reduction; unsaturated fats are preferred for liquid fat applications. Expand
Cardiovascular disease risk of dietary stearic acid compared with trans , other saturated , and unsaturated fatty acids : a systematic review 1 – 4
Background: High stearic acid (STA) soybean oil is a trans-free, oxidatively stable, non-LDL-cholesterol-raising oil that can be used to replace trans fatty acids (TFAs) in solid fat applications.… Expand
Applications of Food Science in Implementing Dietary Lipid Recommendations
This article discusses examples of how food science is being applied to implement 3 dietary lipid recommendations: (1) reduce intake of trans-fatty acids from industrial sources; (2) increase intake… Expand
Supplementation with trans fatty acid at 1% energy did not increase serum cholesterol irrespective of the obesity-related genotypes in healthy adult Japanese.
TLDR
It is indicated that supplementation with 1% energy trans fatty acids has little effect on serum cholesterol in healthy adult Japanese, regardless of genotype of fat mass- and obesity-associated gene or beta-3 adrenergic receptor. Expand
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