Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats.

@article{McCarthyBeckett2002DietarySW,
  title={Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats.},
  author={Donna O McCarthy-Beckett},
  journal={Research in nursing & health},
  year={2002},
  volume={25 1},
  pages={
          49-57
        }
}
Tumor necrosis factor-alpha (TNF) is an immunoregulatory cytokine that plays a major role in tumor-induced anorexia and weight loss. Conjugated linoleic acids (CLA) are naturally occurring isomers of linoleic acid that, when added to the diet, improve food intake and body weight in mice injected with TNF. The purpose of the present study was to examine the effects of a diet supplemented with 0.5% CLA on the nutritional status of rats implanted with the Morris 7777 hepatoma. Body weight, food… CONTINUE READING

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