Dietary supplementation: effects on visual performance and occurrence of AMD and cataracts

@article{Barker2010DietarySE,
  title={Dietary supplementation: effects on visual performance and occurrence of AMD and cataracts},
  author={Felix M. Barker},
  journal={Current Medical Research and Opinion},
  year={2010},
  volume={26},
  pages={2011 - 2023}
}
  • F. M. Barker
  • Published 15 July 2010
  • Medicine
  • Current Medical Research and Opinion
Abstract Objective: To evaluate results of studies that have provided information regarding the effects of dietary supplementation on visual performance, development and progression of age-related macular degeneration (AMD), and risk for cataracts. Research design and methods: Studies with information about the effects of dietary supplementation were identified via PubMed searches that combined (in separate searches) the terms ‘supplement’ OR ‘supplementation’ OR ‘diet’ AND ‘cataract’ or… 

Optimising dietary modification for age-related macular degeneration (AMD)

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Antioxidant vitamins, minerals and cataract: current opinion

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The Pharmacological Effects of Lutein and Zeaxanthin on Visual Disorders and Cognition Diseases

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The Role of Lutein in Eye-Related Disease

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Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?

In these animal models, lutein and zeaxanthin have been reported to have beneficial effects in protecting ocular tissues and cells against damage caused by different etiological factors, including prevention of phototoxic damage by absorption of blue light, reduction of oxidative stress through antioxidant activity and free radical scavenging, and their anti-inflammatory and antiangiogenic properties.

Macular Pigment Optical Density and Its Relationship with Refractive Status and Foveal Thickness in Chinese School-aged Children

Macular pigment optical density was inversely related to MFT and positively related to CFT in Chinese school-age children with low-to-moderate myopia and showed no significant association with age, BMI, IOP, SE or foveal thickness.

Long-term incidence of visual impairment in older persons: associated factors, burden and impacts

The association between diet quality and the incidence of VI, and associations between VI and the subsequent use of support services, subsequent events of falls, fractures, depressive symptoms, and cognitive decline over the short(5 years) and long-terms (10+ years).

Lens protein glycation in diabetic and senile cataract patients

The level of lens glycated protein was found to be significantly increased in subjects of type 2 diabetes mellitus compared to senile cataracts, indicating that glycation of lens protein may play an important role in the development of cataract with greater extent in diabetic patients compared tosenile group.

Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity: a randomized controlled study

  • C. DaniI. Lori Cristiana Germini
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2012
L/Z supplementation was ineffective in preventing ROP in preterm infants and did not affect the outcome at discharge of the authors' patients.

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Vitamins C and E, and lutein/zeaxanthin should be included in the theoretically ideal ocular nutritional supplement, suitable for those with a family history of glaucoma, cataract, or age‐related macular disease, or lifestyle factors predisposing onset of these conditions, such as smoking, poor nutritional status, or high levels of sunlight exposure.

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People older than 55 years should have dilated eye examinations to determine their risk of developing advanced AMD and those with extensive intermediate size drusen, at least 1 large druse, noncentral geographic atrophy in 1 or both eyes, or advanced AMD or vision loss due to AMD in 1 eye should consider taking a supplement of antioxidants plus zinc.
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