Dietary squalene increases tissue sterols and fecal bile acids in the rat

@article{Tilvis1983DietarySI,
  title={Dietary squalene increases tissue sterols and fecal bile acids in the rat},
  author={Reijo Sakari Tilvis and Tatu A. Miettinen},
  journal={Lipids},
  year={1983},
  volume={18},
  pages={32-36}
}
Feeding 1% squalene increased markedly the concentrations of squalene and methyl sterols in each serum lipoprotein class, intestinal mucosa, liver and also in adipose tissue. It also increased cholesterol concentration of the liver and serum VLDL, and esterified cholesterol in serum LDL as well as fecal bile acids. The results suggest that absorbed dietary squalene contributes to some extent to the squalene content of adipose tissue, effectively increases the overall cholesterol synthesis and… CONTINUE READING