Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice.

@article{Duivenvoorden2006DietarySL,
  title={Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice.},
  author={Ilse Duivenvoorden and Peter Jacobus Voshol and Patrick C. N. Rensen and Wim van Duyvenvoorde and Johannes Anthonius Romijn and Jef J. Emeis and Louis M. Havekes and Willem F. Nieuwenhuizen},
  journal={The American journal of clinical nutrition},
  year={2006},
  volume={84 2},
  pages={312-21}
}
BACKGROUND The prevalence of dyslipidemia and obesity resulting from excess energy intake and physical inactivity is increasing. The liver plays a pivotal role in systemic lipid homeostasis. Effective, natural dietary interventions that lower plasma lipids and promote liver health are needed. OBJECTIVE Our goal was to determine the effect of dietary sphingolipids on plasma lipids and liver steatosis. DESIGN APOE*3Leiden mice were fed a Western-type diet supplemented with different… CONTINUE READING

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