Dietary soy protein reduces cardiac lipid accumulation and the ceramide concentration in high-fat diet-fed rats and ob/ob mice.

@article{TorreVillalvazo2009DietarySP,
  title={Dietary soy protein reduces cardiac lipid accumulation and the ceramide concentration in high-fat diet-fed rats and ob/ob mice.},
  author={Ivan Torre-Villalvazo and Fabiola Gonzalez and Carlos A Aguilar-Salinas and Armando R. Tovar and Nimbe Torres},
  journal={The Journal of nutrition},
  year={2009},
  volume={139 12},
  pages={2237-43}
}
Obesity is an epidemic condition strongly associated with cardiovascular morbidity and mortality. Heart disease secondary to obesity is associated with myocardial steatosis, leading to ceramide synthesis and cell dysfunction in a process known as lipotoxicity. Soy protein has been demonstrated to reduce lipotoxicity in the liver and pancreas in different rodent models of obesity. Thus, our purpose in the present work was to assess the effect of dietary soy protein on cardiac lipid accumulation… CONTINUE READING