Dietary sodium affects systemic and renal hemodynamic response to NO inhibition in healthy humans.

@article{Bech1998DietarySA,
  title={Dietary sodium affects systemic and renal hemodynamic response to NO inhibition in healthy humans.},
  author={Jesper N\orgaard Bech and Camilla Birch Nielsen and Per Raml\ov Ivarsen and Kimmo Jensen and Erling Bjerregaard Pedersen},
  journal={American journal of physiology. Renal physiology},
  year={1998},
  volume={274 5},
  pages={F914-F923}
}
Animal studies have indicated that increased nitric oxide (NO) synthesis plays a significant role in the renal adaptation to increased sodium intake. To investigate the role of NO during increased sodium intake in humans, we studied the effect of acute, systemic injection of N G-monomethyl-l-arginine (l-NMMA) on renal hemodynamics [glomerular filtration rate and renal plasma flow (GFR and RPF, respectively)], urinary sodium excretion (FENa), systemic hemodynamics [mean arterial blood pressure… CONTINUE READING

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