Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans.

@article{Verhoef2004DietarySA,
  title={Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans.},
  author={P. N. W. Verhoef and Gery R Steenge and Esther Boelsma and Trinette van Vliet and Margreet Renate Olthof and Martijn Bernard Katan},
  journal={The American journal of clinical nutrition},
  year={2004},
  volume={80 3},
  pages={674-9}
}
BACKGROUND A high plasma total homocysteine (tHcy) concentration is a risk factor for cardiovascular disease. The increase in tHcy induced by methionine, the sole dietary precursor of homocysteine, might be modulated by other amino acids present in dietary proteins. OBJECTIVES Our objectives were to compare the postprandial effect of free and dietary methionine on plasma tHcy concentrations and to investigate whether serine and cystine modify the effect of free methionine on tHcy. DESIGN We… CONTINUE READING
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