Dietary selenium affects methylation of the wobble nucleoside in the anticodon of selenocysteine tRNA([Ser]Sec).

@article{Diamond1993DietarySA,
  title={Dietary selenium affects methylation of the wobble nucleoside in the anticodon of selenocysteine tRNA([Ser]Sec).},
  author={Alan M Diamond and In Seon Choi and Pamela F. Crain and Takeshi Hashizume and Steven C. Pomerantz and Rebecca Cruz and Clifford J. Steer and Kristina E. Hill and Raymond F. Burk and James A. McCloskey and Dolph Lee Hatfield},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 19},
  pages={14215-23}
}
We reported previously that the presence of selenium in culture media of mammalian cells influences both the steady-state levels and distributions of two tRNA isoacceptors involved in the insertion of selenocysteine into protein in response to certain UGA codons. In this study, we demonstrate an increase in the levels of these isoacceptors in rats fed a selenium-adequate diet compared to animals fed a selenium-deficient diet, as well as a shift in the relative distribution toward the tRNA which… CONTINUE READING

From This Paper

Topics from this paper.
34 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…