Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex.

@article{Idrobo1987DietaryRE,
  title={Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex.},
  author={F Idrobo and Kalidas Nandy and David I. Mostofsky and Lawrence Mitchell Blatt and L Nandy},
  journal={Archives of gerontology and geriatrics},
  year={1987},
  volume={6 4},
  pages={355-62}
}
Previous studies have shown increased life span and decreased lipofuscin deposition in brain structures when both premature and young adult animals are calorically restricted of an otherwise nutritionally adequate diet. Three-months-old C57BL/6 mice were subjected to 12 months of caloric restriction (2 g/day), and subsequently exposed to a radial maze… CONTINUE READING