Dietary prebiotics: current status and new definition

@article{Gibson2010DietaryPC,
  title={Dietary prebiotics: current status and new definition},
  author={Glenn R. Gibson and Karen P. Scott and R. A. Rastall and Kieran Michael Tuohy and Arland T. Hotchkiss and Alix Dubert-Ferrandon and M{\'e}lanie G. Gareau and Eileen F. Murphy and Delphine Saulnier and Gunnar Loh and Sandra Macfarlane and Nathalie M. Delzenne and Yehuda Ringel and Gunhild Kozianowski and Robin S. Dickmann and Irene Lenoir-Wijnkoop and Carey Walker and Randal K. Buddington},
  journal={Food Science \& Technology Bulletin: Functional Foods},
  year={2010},
  volume={7},
  pages={1-19}
}
In November 2008, a group of scientists met at the 6th Meeting of the International Scientific Association of Probiotics and Prebiotics (ISAPP) in London, Ontario, Canada, to discuss the functionality of prebiotics. As a result of this, it was concluded that the prebiotic field is currently dominated by gastrointestinal events. However, in the future, it may be the case that other mixed microbial ecosystems may be modulated by a prebiotic approach, such as the oral cavity, skin and the… 
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References

SHOWING 1-10 OF 188 REFERENCES

Probiotics, prebiotics, and synbiotics: approaches for modulating the microbial ecology of the gut.

An overview of how probiotics, prebiotics, and synbiotics may contribute toward nutritional modulation of the gut microecology, with emphasis on the neonatal intestine where appropriate is provided.

Perspectives on the role of the human gut microbiota and its modulation by pro- and prebiotics

Dietary intervention of the human gut microbiota is feasible and has been proven as efficacious in volunteer trials, and the health bonuses of such approaches offer the potential to manage many gut disorders prophylactically.

Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics.

By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.

A Human Volunteer Study to Determine the Prebiotic Effects of Lactulose Powder on Human Colonic Microbiota

Lactulose is shown to be an effective food-grade prebiotic for healthy adults particularly in sections of the community with low bifidobacterial populations and the value of the more direct, culture independent FISH technique in the microbial ecology of the gut has been demonstrated.

The Effect of Probiotics on the Gut Micro-ecology of Farm Animals

Fuller (1989) modified the definition to read ‘A live microbial feed supplement which beneficially affects the host animal by improving its intestinal microbial balance’, which stresses the viable nature of the probiotic and removes the confusion created by the word ‘substances’.

Influence of Dietary Neosugar on Selected Bacterial Groups of the Human Faecal Microbiota

It is demonstrated that supplementing the diet with neosugar influences the relative abundances of selected bacteria with some of the changes consistent with those considered advantageous.

Intestinal microflora of human infants and current trends for its nutritional modulation.

Diet, among other environmental and genetic factors, is currently recognised to have an important role in health and disease. There is increasing evidence that the human colonic microbiota can…

The effect of a prebiotic supplemented formula on growth and stool microbiology of term infants.

Functional food science and gastrointestinal physiology and function

The develop-ment of functional foods for the gut is in its infancy and will be successful only if more fundamental research is done on digestive physiology, the gut microflora, immune system and mucosal function.

Review article: prebiotics in the gastrointestinal tract

It is expected that prebiotics will improve health in a way similar to probiotics, whilst at the same time being cheaper, and carrying less risk and being easier to incorporate into the diet than probiotics.
...