Dietary nitrate improves muscle but not cerebral oxygenation status during exercise in hypoxia.

@article{Masschelein2012DietaryNI,
  title={Dietary nitrate improves muscle but not cerebral oxygenation status during exercise in hypoxia.},
  author={Evi Masschelein and Ruud Van Thienen and Xin-ping Wang and Ann Van Schepdael and Martine A Thomis and Peter Hespel},
  journal={Journal of applied physiology},
  year={2012},
  volume={113 5},
  pages={
          736-45
        }
}
Exercise tolerance is impaired in hypoxia, and it has recently been shown that dietary nitrate supplementation can reduce the oxygen (O(2)) cost of muscle contractions. Therefore, we investigated the effect of dietary nitrate supplementation on arterial, muscle, and cerebral oxygenation status, symptoms of acute mountain sickness (AMS), and exercise tolerance at simulated 5,000 m altitude. Fifteen young, healthy volunteers participated in three experimental sessions according to a crossover… CONTINUE READING

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