Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension.

@article{Carlstrm2011DietaryNA,
  title={Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension.},
  author={Mattias Carlstr{\"o}m and A. Erik G. Persson and Erik G. Larsson and Michael P. Hezel and Peter G Scheffer and Tom Teerlink and Eddie Weitzberg and Jon O Lundberg},
  journal={Cardiovascular research},
  year={2011},
  volume={89 3},
  pages={
          574-85
        }
}
AIMS Reduced bioavailability of endogenous nitric oxide (NO) is a central pathophysiological event in hypertension and other cardiovascular diseases. Recently, it was demonstrated that inorganic nitrate from dietary sources is converted in vivo to form nitrite, NO, and other bioactive nitrogen oxides. We tested the hypothesis that dietary inorganic nitrate supplementation may have therapeutic effects in a model of renal and cardiovascular disease. METHODS AND RESULTS Sprague-Dawley rats… 

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