Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes.

@article{Fisher1990DietaryNF,
  title={Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes.},
  author={Marc Fisher and Peter H. Levine and Bonnie H. Weiner and Mark H. Johnson and Edward M Doyle and Patricia A. Ellis and James J. Hoogasian},
  journal={The American journal of clinical nutrition},
  year={1990},
  volume={51 5},
  pages={804-8}
}
Consuming substantial quantities of n-3 fatty acids reduces atherogenesis in experimental models of atherosclerosis. The mechanisms of this beneficial effect remain uncertain. Monocyte-derived tissue macrophages are associated with atherogenesis, and inhibition of monocyte inflammatory activity could, hypothetically, be helpful in preventing atherosclerosis. We observed that stimulated human monocyte and/or macrophage production of superoxide and the occurrence of monocyte chemiluminescence… CONTINUE READING

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