Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring.

  title={Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring.},
  author={Leena Hilakivi-Clarke and Elisabeth Cho and Ana Cabanes and Sonia DeAssis and Susan E Olivo and William G Helferich and Marc E. Lippman and Robert Clarke},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={8 11},
PURPOSE Against the hypothesis that high estrogen levels in utero increase the risk of developing breast cancer in later life are data showing that pregnancy estrogen levels are significantly higher in Asian women who have low breast cancer risk than in Caucasian women. We investigated whether maternal dietary intake of genistein or n-3 polyunsaturated fatty acids (PUFAs), which are typical to Asian but not Caucasian diet, affect pregnancy estrogen levels and susceptibility to mammary… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 39 extracted citations

The potential contribution of dietary factors to breast cancer prevention

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation • 2017
View 2 Excerpts
Highly Influenced

Environmental Epigenetics

Molecular and Integrative Toxicology • 2015

Lifelong exposure to n-3 PUFA affects pubertal mammary gland development.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme • 2014

The relationship between umbilical cord estrogens and perinatal characteristics.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2014
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 63 references

Similar Papers

Loading similar papers…