Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine.

@article{Paradkar2004DietaryIS,
  title={Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine.},
  author={Prasad N Paradkar and Penny Sue Blum and Mark Alan Berhow and Heinz Baumann and Shiu-Ming Kuo},
  journal={Cancer letters},
  year={2004},
  volume={215 1},
  pages={21-8}
}
Dietary isoflavone intake has been linked to cancer prevention and their anti-inflammation activity was examined. Intraperitoneal lipopolysaccharide (LPS) injection in mice led to a decrease in the liver antioxidant glutathione level but this decrease was prevented in mice fed with an isoflavone-containing diet. Similarly, isoflavone diet prevented the inflammation-associated induction of metallothionein (MT) in the intestine; and the induction of manganese superoxide dismutase (Mn-SOD) in the… CONTINUE READING