Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice.

@article{Kirk1998DietaryIR,
  title={Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice.},
  author={Elizabeth A. Kirk and Patrice Sutherland and Shari A Wang and Alan Chait and Ren{\'e}e C Leboeuf},
  journal={The Journal of nutrition},
  year={1998},
  volume={128 6},
  pages={954-9}
}
Susceptibility to atherosclerosis is determined by a combination of genetic and environmental factors, including diet. Consumption of diets rich in soy protein has been claimed to protect against the development of atherosclerosis. Potential mechanisms include cholesterol lowering, inhibition of lipoprotein oxidation and inhibition of cell proliferation by soy proteins or isoflavones, such as genistein, that are present in soy. This study was designed to determine whether soy isoflavones confer… CONTINUE READING

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