Dietary influences on urinary oxalate and risk of kidney stones.

  title={Dietary influences on urinary oxalate and risk of kidney stones.},
  author={Linda K. Massey},
  journal={Frontiers in bioscience : a journal and virtual library},
  • L. Massey
  • Published 1 May 2003
  • Medicine
  • Frontiers in bioscience : a journal and virtual library
Calcium oxalate is the most common constituent of kidney stones. Increases in urinary oxalate increase risk of calcium oxalate supersaturation more than increases in urinary calcium, as the physiological level of oxalate is about one-fifth to one-tenth that of urinary calcium. Urinary oxalate derives from two sources: endogenous synthesis and diet. Endogenous synthesis is proportional to lean body mass, and cannot be altered by any current treatment. Dietary oxalate is found in all plant foods… 

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The results suggest that the intestinal absorption of dietary oxalates makes a substantial contribution to urinary oxalate excretion and that this absorption can be modified by decreasing oxalATE intake or increasing the intakes of calcium, magnesium, and fiber.

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