Dietary glucosylceramide improves skin barrier function in hairless mice.

@article{Tsuji2006DietaryGI,
  title={Dietary glucosylceramide improves skin barrier function in hairless mice.},
  author={Kiyomi Tsuji and Susumu Mitsutake and Junko Ishikawa and Yutaka Takagi and Masashi Akiyama and Hiroshi Shimizu and Takahiro Tomiyama and Yasuyuki Igarashi},
  journal={Journal of dermatological science},
  year={2006},
  volume={44 2},
  pages={
          101-7
        }
}
BACKGROUND Sphingolipids are known to play an important role in both water retention and epidermal permeability barrier function in mammalian stratum corneum. However, little is known about the effects on epidermal function of orally administered sphingolipids. OBJECTIVE We examined the effect of dietary glucosylceramide (GluCer) on the maintenance and recovery of epidermal barrier function. METHODS Hairless mice were fed a particular diet (HR-AD) for 4 weeks to induce chronic skin… CONTINUE READING
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