Dietary fructooligosaccharides affect intestinal barrier function in healthy men.

@article{Bruggencate2006DietaryFA,
  title={Dietary fructooligosaccharides affect intestinal barrier function in healthy men.},
  author={Sandra J M ten Bruggencate and Ingeborg M. J. Bovee-Oudenhoven and Mischa L G Lettink-Wissink and Martijn Bernard Katan and Roelof van der Meer},
  journal={The Journal of nutrition},
  year={2006},
  volume={136 1},
  pages={70-4}
}
In contrast to most expectations, we showed previously that dietary fructooligosaccharides (FOS) stimulate intestinal colonization and translocation of invasive Salmonella enteritidis in rats. Even before infection, FOS increased the cytotoxicity of fecal water, mucin excretion, and intestinal permeability. In the present study, we tested whether FOS has these effects in humans. A double-blind, placebo-controlled, crossover study of 2 x 2 wk, with a washout period of 2 wk, was performed with 34… CONTINUE READING