Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells.

@article{Ramadass2003DietaryFM,
  title={Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells.},
  author={Pachaikani Ramadass and Purushothaman Meerarani and Michal Toborek and Larry W Robertson and Bernhard Hennig},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2003},
  volume={76 1},
  pages={212-9}
}
Polychlorinated biphenyls (PCBs), especially the more coplanar PCBs, have been shown to induce oxidative stress, various transcription factors, and subsequent inflammatory processes critical to atherosclerosis in vascular endothelial cells. Dietary flavonoids such as catechins and quercetin possess antioxidant and anti-inflammatory properties. To test the hypothesis that flavonoids can modify PCB-mediated endothelial cytotoxicity, endothelial cells were treated with epigallocatechin-3-gallate… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 52 references

Background levels in humans

A. A. Jensen
Halogenated Biphenyls , Terphenyls , Naphthalenes , Dibenzodioxins , and Related Products • 1989
View 2 Excerpts
Highly Influenced

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.

Critical reviews in food science and nutrition • 2003
View 3 Excerpts

Direct scavenging of nitric oxide and superoxide by green tea.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2002
View 1 Excerpt

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