Dietary fish oil aggravates paracetamol-induced liver injury in mice.

Abstract

BACKGROUND Paracetamol (APAP) hepatotoxicity remains the leading cause of drug-induced liver failure. Fish oil, which contains ω-3 fatty acids, has demonstrated therapeutic efficacy in several models of liver disease. Evidence for its use in APAP intoxication, however, is conflicting. The effects of fish oil supplementation on APAP-induced liver failure… (More)
DOI: 10.1177/0148607112450735

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