Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the ApcMin/+ model of colon cancer

Abstract

Thrombospondin 1 is a glycoprotein that regulates cellular phenotype through interactions with its cellular receptors and extracellular matrix-binding partners. Thrombospondin 1 locally regulates angiogenesis and inflammatory responses that contribute to colorectal carcinogenesis in ApcMin/+ mice. The ability of thrombospondin 1 to regulate responses of… (More)
DOI: 10.1038/oncsis.2016.37

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Cite this paper

@inproceedings{SotoPantoja2016DietaryFO, title={Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the ApcMin/+ model of colon cancer}, author={David R. Soto-Pantoja and Jennifer Sipes and Gema Martin-Manso and Brian M. Westwood and Nichole L. Morris and A. Ghosh and Nancy J. Emenaker and Donna Roberts}, booktitle={Oncogenesis}, year={2016} }