Dietary factors in functional dyspepsia

  title={Dietary factors in functional dyspepsia},
  author={Christine Feinle-Bisset and Michael Horowitz},
  journal={Neurogastroenterology \& Motility},
Abstract  Functional dyspepsia (FD) is characterized by upper gastrointestinal symptoms, which are frequently exacerbated by meal ingestion. While subgroups of FD patients exhibit a range of disturbances in upper gastrointestinal motor function, including delayed gastric emptying and abnormal intragastric meal distribution, which may reflect impaired proximal gastric relaxation and/or antral dysmotility, the association between symptoms and abnormalities in motor function appears to be… 

Diet and Nutritional Management in Functional Gastrointestinal Disorder: Functional Dyspepsia

Evidence is lacking, as the majority of studies have been retrospective; moreover, the results are inconsistent, and prospective studies are necessary to formulate reliable dietary guidelines for patients with dyspepsia.

Dietary and lifestyle factors in functional dyspepsia

A number of options could be used as starting points for meaningful large-scale studies in the future evaluating the potential beneficial effect of dietary interventions and changes in lifestyle on patients with functional dyspepsia.

Food and functional dyspepsia: a systematic review

Wheat and dietary fats may play key roles in the generation of FD symptoms and reduction or withdrawal eased symptoms and Randomised trials investigating the roles of gluten, FODMAPs and high fat ingestion and naturally occurring food chemicals are warranted.

Role of the Duodenum in the Pathogenesis of Functional Dyspepsia: A Paradigm Shift

The hypothesis that FD is a disorder of microscopic small intestinal inflammation in a major subset is gaining acceptance, opening the possibility of novel treatment approaches that may be able to alter the natural history of the disorder.

Current understanding of pathogenesis of functional dyspepsia

Understanding FD offers a glimpse into the nature of functional gastrointestinal disorders in general, as motility abnormalities and visceral hypersensitivity are thought to be important in the manifestation of FD symptoms, but the other factors are also thought to contribute by interacting and modifying motility and visceral sensitivity.

Treatment of Functional Dyspepsia and Gastroparesis

Treatment options for functional dyspepsia and GP are focused on, with an emphasis on new advances in the field over the last several years, including medications for visceral pain and nausea.

Dietary and lifestyle factors in functional

A number of options could be used as starting points for meaningful large-scale studies in the future evaluating the potential beneficial effect of dietary interventions and changes in lifestyle on patients with functional dyspepsia.

Nutrient Intake and Dietary Behaviors of Patients with Functional Dyspepsia

The results indicate that functional dyspepsia patients' nutritional status by consumption of nutrients was at a level of normal healthy peo-ple and that dietary habits were better than normal adults, however, their fat intake levels were somewhat higher than normal people.

Dietary fat intake and functional dyspepsia

It seems that a reduction in intake of fatty foods may useful, although this requires more evaluations.

The Role of Diet in the Management of Non-Ulcer Dyspepsia

Some foods, especially spicy, pickled, and high-fat foods, strongly induced dyspepsia and aggravated the symptoms in dyspeptic patients.



Pathophysiology and treatment of functional dyspepsia.

In a study in 30 H. pylori-negative patients with functional dyspepsia ranitidine (150 mg bid) significantly reduced the severity of heartburn, and was most pronounced in patients of the reflux-like subgroup.

Cholecystokinin Hyperresponsiveness in Dysmotility‐Type Nonulcer Dyspepsia

An altered response to CCK may possibly be responsible for the dyspeptic symptoms in nonulcer dyspepsia and may be associated with the frequently observed abnormal gastric motility.

The proximal stomach and postprandial symptoms in functional dyspeptics

There was no clear relationship between any of the 15 Nepean Dyspepsia Index symptoms and proximal stomach function.

Effects of Duodenal Lipids on Gastric Sensitivity and Relaxation in Patients with Ulcer-Like and Dysmotility-Like Dyspepsia

Investigating gastric sensorimotor function after duodenal lipid infusion, FD patients can accurately be differentiated from HC, and impaired fundic relaxation seems to be more common in patients with ULD.

Symptoms associated with hypersensitivity to gastric distention in functional dyspepsia.

The increase of intra-balloon pressure over intra-abdominal pressure needed to induce discomfort or pain is the most appropriate expression of sensitivity to gastric distention because it yields a meaningful lower range of normal and it is independent from age and body mass index.

Role of stress in functional gastrointestinal disorders. Evidence for stress-induced alterations in gastrointestinal motility and sensitivity.

In experimental animals the most consistent pattern of GI motor alterations induced by various psychological and physical stressors is that of delaying gastric emptying and accelerating colonic transit, which suggests that stress affects visceral sensitivity in humans.

Functional dyspepsia symptoms, gastric emptying and satiety provocative test: analysis of relationships.

The satiety test gives a fine numerical measure of satiety and confirms the results of a symptoms questionnaire, and showed an indirect correlation between severity of early satiety--as measured by the satieties test, and gastric emptying rate, as well as an association between bloating and delayed gastric emptied.

Plasma acylated ghrelin levels correlate with subjective symptoms of functional dyspepsia in female patients

The correlation of circulating acylated ghrelin levels with the subjective symptom score and the A/D ratio in FD patients suggest that acylate gh Relin may play a role in the pathophysiology of FD.

Chemospecific alterations in duodenal perception and motor response in functional dyspepsia

In functional dyspepsia alterations in sensor and motor responses to intraduodenal acid and nutrients are chemospecific, suggesting an abnormality at the level of visceral afferents or mucosal chemoreceptors in these patients.