Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.

@article{Chassaing2017DietaryED,
  title={Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.},
  author={Benoit Chassaing and Tom Richard Van de Wiele and Jana De Bodt and Massimo Marzorati and Andrew T. Gewirtz},
  journal={Gut},
  year={2017},
  volume={66 8},
  pages={
          1414-1427
        }
}
OBJECTIVE The intestinal microbiota plays a central role in the development of many chronic inflammatory diseases including IBD and metabolic syndrome. Administration of substances that alter microbiota composition, including the synthetic dietary emulsifiers polysorbate 80 (P80) and carboxymethylcellulose (CMC), can promote such inflammatory disorders. However, that inflammation itself impacts microbiota composition has obfuscated defining the extent to which these compounds or other… CONTINUE READING

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A new real - time PCR assay for accurate quanti fi cation of the individual members of the Altered Schaedler Flora microbiota in gnotobiotic mice

  • JC Gomes-Neta, S Mantz, K Held
  • J Microbiol Methods
  • 2017