Dietary eicosapentaenoic acid does not modify cyclosporin-induced inhibition of angiotensin II-stimulated prostaglandin synthesis in mesangial cells.

Abstract

Clinical and experimental cyclosporin A (CSA) nephrotoxicity is characterized by alterations in renal hemodynamics and a reduction in glomerular filtration rate (GFR). The mesangial cell may be a target for the actions of CSA. CSA has been shown to activate the renin angiotensin system and to increase the excretion of TXB2 (the stable metabolite of TXA2… (More)

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@article{Walker1989DietaryEA, title={Dietary eicosapentaenoic acid does not modify cyclosporin-induced inhibition of angiotensin II-stimulated prostaglandin synthesis in mesangial cells.}, author={R. J. Walker and Victor Lazzaro and Geoff Duggin and Judit Horv{\'a}th and David J Tiller}, journal={Renal failure}, year={1989}, volume={11 2-3}, pages={125-32} }