Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity.

  title={Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity.},
  author={C S Yang and John F. Brady and Jungil Hong},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={6 2},
The levels and activities of cytochrome P450 enzymes are influenced by a variety of factors, including the diet. In this article, the effects of selected non-nutritive dietary chemicals, macronutrients, micronutrients, and ethanol on cytochromes P450 and xenobiotic metabolism are reviewed in the light of our current understanding of the multiplicity and substrate specificity of cytochrome P450 enzymes. Although the mechanisms of action of several dietary chemicals on specific cytochrome P450… CONTINUE READING
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