Dietary compared with blood concentrations of carotenoids and breast cancer risk: a systematic review and meta-analysis of prospective studies.

@article{Aune2012DietaryCW,
  title={Dietary compared with blood concentrations of carotenoids and breast cancer risk: a systematic review and meta-analysis of prospective studies.},
  author={Dagfinn Aune and Doris S. M. Chan and Ana Rita Vieira and Deborah A. Navarro Rosenblatt and Rui Vieira and Darren Charles Greenwood and Teresa Norat},
  journal={The American journal of clinical nutrition},
  year={2012},
  volume={96 2},
  pages={
          356-73
        }
}
  • D. Aune, D. Chan, +4 authors T. Norat
  • Published 1 August 2012
  • Medicine
  • The American journal of clinical nutrition
BACKGROUND Measurement errors in the dietary assessment of fruit and vegetable intake may attenuate associations with breast cancer risk and might explain the weak associations observed in epidemiologic studies. Carotenoid concentrations in blood are biomarkers of fruit and vegetable intake; however, no systematic assessment has compared dietary intake with blood concentrations of carotenoids and breast cancer risk. OBJECTIVE We conducted a systematic review and meta-analysis of prospective… 
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Highly Influential Citations
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Citation Type

Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies
TLDR
The results support recommendations to increase fruit and vegetable intake, but not antioxidant supplement use, for chronic disease prevention and higher dietary intake and/or blood concentrations of vitamin C, carotenoids, and α-tocopherol were associated with reduced risk of cardiovascular disease, total cancer, and all-cause mortality.
Dietary and circulating vitamin C, vitamin E, β-carotene and risk of total cardiovascular mortality: a systematic review and dose–response meta-analysis of prospective observational studies
TLDR
It is demonstrated that higher vitamin C intake and higher circulating concentrations of vitamin C, vitamin E and β-carotene are associated with a lower risk of CVD mortality.
Specific carotenoid intake is inversely associated with the risk of breast cancer among Chinese women
TLDR
It is indicated that a greater intake of specific carotenoids was associated with a decreased risk of breast cancer among Chinese women residing in Guangdong.
Dietary total antioxidant capacity and the risk of breast cancer: a case-control study.
TLDR
This study supports a protective effect of dietary antioxidants in relation to breast cancer risk, and food selection based on TAC of foods may be an effective strategy to modify the risk of cancer.
Association of carotenoids with risk of gastric cancer: A meta-analysis.
Total dietary antioxidant capacity, individual antioxidant intake and breast cancer risk: The Rotterdam study
TLDR
High overall dietary antioxidant capacity is associated with a lower risk of breast cancer, and individual effects of dietary carotenoids and dietary flavonoids may be restricted to subgroups such as smokers and elderly.
Healthy Dietary Patterns and the Risk of Breast Cancer: A Review of Current Data
TLDR
Protective effects of healthy dietary patterns against breast cancer were mainly observed in women with normal body weight (BMI<25 kg/m2), and further studies are required to clear the associations of dietary patterns and breast cancer risk.
WHO EMRO | Dietary total antioxidant capacity and the risk of breast cancer: a case–control study
TLDR
This study supports a protective effect of dietary antioxidants in relation to breast cancer risk by showing that consumption of fruits and vegetables with higher TAC was associated with a significantly decreased risk of breast cancer.
Is There an Association between β-Carotene and Breast Cancer? A Systematic Review on Breast Cancer Risk
TLDR
The evidence from the included studies confirms that there is an association between β-carotenoids and breast cancer risk; the dietary intake of β- carotenoid may be beneficial in reducing the risk of developing breast cancer.
Plasma carotenoids and breast cancer risk in the Cancer Prevention Study II Nutrition Cohort
TLDR
It is suggested that higher plasma α-carotene is associated with lower risk of invasive breast cancer, compared with other plasma carotenoids and total fruit and vegetable intake.
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  • Medicine
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