Dietary canola oil suppressed growth of implanted MDA-MB 231 human breast tumors in nude mice.

@article{Hardman2007DietaryCO,
  title={Dietary canola oil suppressed growth of implanted MDA-MB 231 human breast tumors in nude mice.},
  author={Wm. Hardman},
  journal={Nutrition and cancer},
  year={2007},
  volume={57 2},
  pages={
          177-83
        }
}
Long chain omega 3 (n-3) fatty acids, eicosapentaenoic (EPA) and/or docosahexaenoic acid (DHA), have been shown to suppress growth of most cancer cells. In vivo, alpha linolenic acid (ALA, 18:3n-3) can be converted to EPA or DHA. We hypothesized that substituting canola oil (10% ALA) for the corn oil (1% ALA) in the diet of cancer bearing mice would slow tumor growth by increasing n-3 fatty acids in the diet. Sixty nude mice received MDA-MB 231 human breast cancer cells and were fed a diet… CONTINUE READING

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