Dietary calcium supplementation increases apoptosis in the distal murine colonic epithelium.

BACKGROUND Increased dietary calcium might reduce colorectal cancer risk, possibly by reduction of colonic epithelial hyperproliferation, but not all studies have demonstrated this. Little is known about the effects of calcium on colonic apoptosis. AIM To quantify the effects of increasing calcium on apoptosis and cell proliferation in normal murine… CONTINUE READING