Corpus ID: 23651035

Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis.

@article{BenitoGarcia2006DietaryCI,
  title={Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis.},
  author={E. Benito-Garcia and J. E. Heller and L. Chibnik and N. Maher and H. Matthews and Jessica A Bilics and M. Weinblatt and N. Shadick},
  journal={The Journal of rheumatology},
  year={2006},
  volume={33 7},
  pages={
          1275-81
        }
}
OBJECTIVE Methylxanthines, like caffeine, have been thought to reverse the antiinflammatory effects of methotrexate (MTX) in rheumatoid arthritis (RA). We investigated whether patients with RA taking MTX with a higher dietary caffeine intake have a worse clinical response to MTX than those with a lower intake. METHODS Patients with RA enrolled in a prospective cohort study and currently taking MTX were divided equally into low, moderate, and high caffeine consumers. MTX clinical response was… Expand
Does caffeine intake affect methotrexate efficacy?
  • G. Alarcón
  • Medicine
  • Nature Clinical Practice Rheumatology
  • 2006
The Effect of Methotrexate in Rheumatoid Arthritis Patients is Reduced by Tea Consumption
Hidden Questions on Methotrexate
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