Dietary beta-carotene protects lung and liver parenchyma of rats treated with monocrotaline.

@article{Baybutt1999DietaryBP,
  title={Dietary beta-carotene protects lung and liver parenchyma of rats treated with monocrotaline.},
  author={Richard Carleton Baybutt and Agostino Molteni},
  journal={Toxicology},
  year={1999},
  volume={137 2},
  pages={69-80}
}
Some studies have indicated that the injury induced by the hepato- and pneumotoxin monocrotaline (MCT) is in part mediated by oxidation. Because beta-carotene is a potent antioxidant, we hypothesized that it would protect the lung and liver parenchyma against MCT-induced injury. Twenty rats were assigned randomly to four groups. All rats were fed a standard AIN93G diet with or without beta-carotene. After 1 week on the purified diets, half of the rats fed the control (standard) diet and half of… CONTINUE READING
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