Dietary antioxidant supplementation combined with quercetin improves cycling time trial performance.

  title={Dietary antioxidant supplementation combined with quercetin improves cycling time trial performance.},
  author={Holden S H Macrae and Kari Mefferd},
  journal={International journal of sport nutrition and exercise metabolism},
  volume={16 4},
  • H. MacraeKari Mefferd
  • Published 1 August 2006
  • Psychology
  • International journal of sport nutrition and exercise metabolism
We investigated whether 6 wk of antioxidant supplementation (AS) would enhance 30 km time trial (TT) cycling performance. Eleven elite male cyclists completed a randomized, double-blind, cross-over study to test the effects of twice daily AS containing essential vitamins plus quercetin (FRS), and AS minus quercetin (FRS-Q) versus a baseline TT (B). MANOVA analysis showed that time to complete the 30 km TT was improved by 3.1% on FRS compared to B (P < 0.01), and by 2% over the last 5 km (P < 0… 

Figures and Tables from this paper

Long-term quercetin supplementation reduces lipid peroxidation but does not improve performance in endurance runners

Evidence suggests that quercetin can reduce oxidative stress (lipid peroxidation), however, performance improvements were not significant (as measured by VO2peak, running economy, heart rate, and RPE).

Effects of six weeks of quercetin supplementation on physical performance in ROTC cadets.

Six weeks of dietary quercetin supplementation in moderately trained individuals conducting military physical training did not improve VO(2peak) or performance on the APFT, BMPU, WAnT, and 36.6-m sprint.

Dietary quercetin supplementation does not increase maximal oxygen uptake and physical work capacity

It is concluded that dietary quercetin supplementation with 1 g/d for 8 wk in non-endurance-trained men and women does not increase VO2peak or physical work capacity.

The Dietary Combination of Quercetin and Resveratrol Supplementation May Improve Exercise Tolerance in Young Untrained Males by Modulating IL-6 and NGAL Response

The results suggest that dieatary combination of quercetin and resveretrol may act as a potential tool for enhancing exercise performance by regulation IL-6, NGAL level in untrained men.

The dietary flavonoid quercetin increases VO(2max) and endurance capacity.

It is suggested that as little as 7 days of quercetin supplementation can increase endurance without exercise training in untrained participants, which may have important implications for enhancement of athletic and military performance.

Quercetin's influence on exercise performance and muscle mitochondrial biogenesis.

Plasma Q levels rose significantly in Q versus P during the 2-wk supplementation period, and there were modest but insignificant increases in the relative copy number of mitochondrial DNA and messenger RNA levels of four genes related to mitochondrial biogenesis.

Impact of Polyphenol Antioxidants on Cycling Performance and Cardiovascular Function

Polyphenol antioxidant supplementation had no impact on exercise performance and did not alter the cardiovascular or thermoregulatory responses to exercise in the heat.

Quercetin Supplementation Does Not Attenuate Exercise Performance and Body Composition in Young Female Swimmers

It is concluded that quercetin supplementation (1000 g/day) for 8 weeks in female athletes didn't show any significant association with exercise performance.

Quercetin's effect on cycling efficiency and substrate utilization.

  • C. DumkeD. Nieman L. McAnulty
  • Biology
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2009
The data indicate that GE is reduced during an exhausting 3-h bout of exercise, however, quercetin did not significantly affect any outcomes in these already well-trained subjects.

Ergogenic effects of quercetin supplementation in trained rats

This study showed no effects inVO2 peak, speed at VO2 peak or endurance time to exhaustion after six weeks of quercetin supplementation compared with placebo in trained rats, and quercETin was show to increase blood lactate production after high-intensity exercise.



Antioxidant supplementation enhances neutrophil oxidative burst in trained runners following prolonged exercise.

The data suggest that antioxidant supplementation may be of benefit to endurance athletes for the maintenance of this particular function of the innate immune system following the 7-day supplementation period.

The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: results from a placebo-controlled double-blind study in cyclists

It is suggested that in moderately trained cyclists, antioxidant supplementation counters oxidative stress induced by a 90 min exercise at 70% $${\dot{{\it V}}}{\text{O}}_{2\max}.$$

Effect of altering substrate availability on metabolism and performance during intense exercise.

Increased fat availability during intense cycling increases the rate of fat oxidation; but the reduction in the rates of carbohydrate oxidation in the presence of high circulating plasma free FA is unlikely to enhance intense exercise performance lasting about 1 h.

Metabolic and performance responses during endurance exercise after high-fat and high-carbohydrate meals.

The results suggest that, although the availability of fatty acids and other substrates in plasma can be markedly altered by dietary means, the pattern of substrate oxidation during endurance exercise is remarkably resistant to alteration.

Clinical Pharmacokinetics of Antioxidants and Their Impact on Systemic Oxidative Stress

This article addresses data provided from clinical trials, highlighting the clinical pharmacokinetics of vitamin C, vitamin E, β-carotene, lycopene, lutein, quercetin, rutin, catechins and selenium.

Generation of reactive oxygen species after exhaustive aerobic and isometric exercise.

There was evidence of oxidative stress after both exhaustive aerobic and isometric exercise, and lipid hydroperoxides, protein carbonyls, and total antioxidants increased after both IE and AE.

The effects of acute exercise on neutrophils and plasma oxidative stress.

Exercise intensity plays a major role in postexercise blood oxidative stress, whereas total exercise energy expenditure does not, and neutrophils recruited into circulation during exercise may impose a threshold dependent oxidative stress in blood plasma after exercise.

Spin-trappers and vitamin E prolong endurance to muscle fatigue in mice.