Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects.

@article{Zhao2007DietaryAA,
  title={Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects.},
  author={Guixiang Zhao and Terry D. Etherton and Keith R. Martin and Peter J. Gillies and Sheila G West and Penny M. Kris-Etherton},
  journal={The American journal of clinical nutrition},
  year={2007},
  volume={85 2},
  pages={
          385-91
        }
}
BACKGROUND Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in alpha-linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hypercholesterolemic subjects. OBJECTIVE The objective was to evaluate the effects of a diet high in ALA on serum proinflammatory cytokine concentrations and cytokine production by cultured peripheral blood mononuclear cells (PBMCs) from subjects fed the experimental diets. DESIGN A… Expand

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