Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.

@article{Morowitz2017DietarySW,
  title={Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.},
  author={Michael J Morowitz and Valentina Di Caro and Diana Pang and Jessica L. Cummings and Brian A. Firek and Matthew B Rogers and Sarangarajan Ranganathan and Robert S. B. Clark and Rajesh K. Aneja},
  journal={Critical care medicine},
  year={2017},
  volume={45 5},
  pages={
          e516-e523
        }
}
OBJECTIVES Links between microbial alterations and systemic inflammation have been demonstrated in chronic disease, but little is known about these interactions during acute inflammation. This study investigates the effect of dietary supplementation with cellulose, a nonfermentable fiber, on the gut microbiota, inflammatory markers, and survival in two murine models of sepsis. DESIGN Prospective experimental study. SETTING University laboratory. SUBJECTS Six-week-old male C57BL/6 wild… CONTINUE READING
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