Dietary Restriction in Drosophila: Delayed Aging or Experimental Artefact?

  title={Dietary Restriction in Drosophila: Delayed Aging or Experimental Artefact?},
  author={Matthew W D Piper and Linda Partridge},
  journal={PLoS Genetics},
  pages={37 - 55}
Lifespan can be extended by reduction of dietary intake. This practice is referred to as dietary restriction (DR), and extension of lifespan by DR is evolutionarily conserved in taxonomically diverse organisms including yeast, invertebrates, and mammals. Although these two often-stated facts carry the implication that the mechanisms of DR are also evolutionarily conserved, extension of lifespan could be a case of evolutionary convergence, with different underlying mechanisms in different taxa… CONTINUE READING

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The retardation of aging and disease by dietary restriction

  • R Weindruch, RL Walford
  • Springfield (Illinois): Thomas
  • 1988
Highly Influential
3 Excerpts

Optimization of dietary resitrction protocols for Drosophila to avoid food toxicity

  • TM Bass, MD Piper, RC Grandison, R Wong, P Martinez
  • J Gerontol. In press
  • 2007
1 Excerpt

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