Dietary Luteolin Reduces Proinflammatory Microglia in the Brain of Senescent Mice.

Abstract

Brain microglia become dysregulated during aging and express proinflammatory cytokines that play a role in cognitive aging. Recent studies suggest the flavonoid luteolin reduces neuroinflammation and improves learning and memory in aged mice. However, if dietary luteolin reduces microglia activity in the brain of senescent mice is not known. We hypothesized… (More)
DOI: 10.1089/rej.2015.1708

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