Diet modification affects DNA oxidative damage in healthy humans.

  title={Diet modification affects DNA oxidative damage in healthy humans.},
  author={Lin Chen and Phyllis E. Bowen and D Berzy and F Aryee and Maria Stacewicz-Sapuntzakis and Rosemary E Riley},
  journal={Free radical biology & medicine},
  volume={26 5-6},
DNA 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a promising biomarker for oxidative damage. We assessed its responsiveness to diet in 32 nonsmoking, healthy subjects (12 male, 20 female) aged 31+/-7.6 years. They consumed two liquid formula diets (Ensures) as the sole source of nutrition for 10-d in a randomized crossover design, with 5-d control solid food diets as washout before each liquid diet period. Reformulated Ensure (Re-En) had a vitamin E/ PUFA of 3.5 compared to standard Ensure (En) of 1… CONTINUE READING

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