Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation.

@article{Okada2009DietinducedUO,
  title={Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation.},
  author={Yuko Okada and Hiroshi Sakaue and Tomoki Nagare and Masato Kasuga},
  journal={The Kobe journal of medical sciences},
  year={2009},
  volume={54 5},
  pages={E241-9}
}
The expansion of white adipose tissue (WAT) mass during the development of obesity is mediated in part through an increase in adipocyte size. Although gene expression profiles associated with adipogenesis in vitro and the development of obesity in vivo have been characterized by DNA microarray analysis, the role of chromatin and chromatin-modifying proteins in the regulation of gene expression related to adipocyte hypertrophy has remained unclear. We have now shown that maintenance of C57BL/6J… CONTINUE READING

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ANALYSIS OF DNA METHYLATION IN OBESTGENIC GENES E249 and Kozak, L.P

  • R. A. Koza, L. Nikonova, +4 authors J. Skaf
  • PLoS Genet
  • 2006
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