Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload

Abstract

Heart failure (HF) is the end stage of cardiovascular disease, in which hypertrophic remodeling no longer meets cardiac output demand. Established animal models of HF have provided insights into disease pathogenesis. However, these models are developed on dissimilar metabolic backgrounds from humans - patients with HF are frequently overweight or obese… (More)
DOI: 10.14814/phy2.12489

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Cite this paper

@inproceedings{Holzem2015DietinducedOP, title={Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload}, author={Katherine M. Holzem and Joseph T Marmerstein and Eli J Madden and Igor R. Efimov}, booktitle={Physiological reports}, year={2015} }