Diet-induced obese rats have higher iron requirements and are more vulnerable to iron deficiency

@article{Bertinato2014DietinducedOR,
  title={Diet-induced obese rats have higher iron requirements and are more vulnerable to iron deficiency},
  author={Jesse Bertinato and Cristina Aroche and Louise J. Plouffe and Megan Maureen Lee and Zehra Murtaza and Laura S Kenney and Christopher Bernard Lavergne and Alfred Antoine Aziz},
  journal={European Journal of Nutrition},
  year={2014},
  volume={53},
  pages={885-895}
}
PurposeSince obesity is associated with poorer iron status, the effects of diet-induced obesity on iron status and iron-regulatory pathways were examined.MethodsWeanling male diet-induced obese sensitive (n = 12/diet group) and resistant (n = 12/diet group) rats were fed one of four high-fat, high-energy diets supplemented with 5 (5Fe, low), 15 (15Fe, marginal), 35 (35Fe, normal) or 70 (70Fe, high) mg iron/kg diet for 12 weeks. At the end of the study, rats in each diet group were categorised… CONTINUE READING
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