Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs.

@article{Sangild2006DietAC,
  title={Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs.},
  author={Per Torp Sangild and Richard H. Siggers and Mette H Schmidt and Jan Elnif and Charlotte Reinhard Bjornvad and Thomas Thymann and Marie L Grondahl and Axel Kornerup Hansen and Soeren K Jensen and M. -A. -D. Boye and Lars Moelbak and Randal K. Buddington and B Westr{\"o}m and Jens Juul Holst and Douglas Burrin},
  journal={Gastroenterology},
  year={2006},
  volume={130 6},
  pages={1776-92}
}
BACKGROUND & AIMS Preterm birth and formula feeding are key risk factors associated with necrotizing enterocolitis (NEC) in infants, but little is known about intestinal conditions that predispose to disease. Thus, structural, functional, and microbiologic indices were used to investigate the etiology of spontaneous NEC development in preterm pigs. METHODS Piglets were delivered by cesarean section at 92% gestation, reared in infant incubators, and fed infant formula or colostrum every 3… CONTINUE READING
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