Diet, microorganisms and their metabolites, and colon cancer

@article{OKeefe2016DietMA,
  title={Diet, microorganisms and their metabolites, and colon cancer},
  author={Stephen J. D. O'Keefe},
  journal={Nature Reviews Gastroenterology &Hepatology},
  year={2016},
  volume={13},
  pages={691-706}
}
Colorectal cancer is one of the so-called westernized diseases and the second leading cause of cancer death worldwide. On the basis of global epidemiological and scientific studies, evidence suggests that the risk of colorectal cancer is increased by processed and unprocessed meat consumption but suppressed by fibre, and that food composition affects colonic health and cancer risk via its effects on colonic microbial metabolism. The gut microbiota can ferment complex dietary residues that are… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 200 REFERENCES

Coffee Consumption and the Risk of Colorectal Cancer.

  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 2016

Effects of an high-fat diet enriched in lard or in fish oil on the hypothalamic amp-activated protein kinase and inflammatory mediators

E Viggiano
  • Front. Cell. Neurosci. 10,
  • 2016

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

S Beyaz
  • Nature 531,
  • 2016

High-fat diets rich in dietary saturated fat protect against azoxymethane/dextran sulfate sodium induced colon cancer

Enos, T R.
  • Am. J. Physiol. Gastrointest. Liver Physiol. 310,
  • 2016